A 53 year old lady presented with recurrent erythematous papules, ulcerating nodules of the intertriginous areas and crusted plaques of the scalp for 3 years duration. She has been clinically diagnosed and treated for hidradenitis suppurativa and dissecting cellulitis of the scalp. Poor response to therapy prompted us to arrange histological evaluation (Figure 1). Extensive evaluation with biochemical, histological and radiological workup was arranged in order to out the systemic involvement. She was found to have complete cranial diabetes insipidus, but there were no liver, lung or bone marrow involvement. she was referred to oncologist, started on chemotherapy with a satisfactory response Langerhans cell histiocytosis (LCH), is a clonal proliferative disorder of bone marrow-derived histiocytes with three sub types(1) (single-system unifocal, single-system multifocal, and multisystem disease). .
2023-01-01.
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