The autoimmune bullous diseases (AIBD) are a group of clinical conditions characterized by erosions and bullae of the skin and mucous membranes, which can be prolonging to serious concerns for patients in their activities of daily living (ADL) and adversely affect their quality of life. Descriptive cross - sectional study design was conducted in dermatology clinic at National Hospital Colombo. 121 participants more than 18 years old were included. Non-probability, consecutive sampling technique was used to collect the study sample. Interviewer-administered questionnaire included with dermatological quality of life index was used as study instrument. Most prevalent bullous disorder is pemphigus vulgaris (N=81:66.9%). Extremely larger effect was created on the quality of life of significant majority of the study participants due to the disease condition (N=80 ;66.1%). Highest effect on quality of life after treatments was created on PV patients (t=17.08: p<0.001). Majority of participants represented extensive disease severity scores (N=99:81.8%) at initial presentation. Participants who had significant disease severity at the end of the treatments (N=15:12.4%) showed moderate and large improvement of quality of life. Majority of the study participants had reduced disease severity with treatment (Z>1.96:p<0.001). Majority of the study participants had detected side effects during the first two months following commencement of treatment. 62.8% (N=76) had experienced remission episodes of the disease condition. Age above 50 years (OR=2.75:95%CI=1.26-5.95), Patients with significant initial disease severity (OR=3.82:95%CI=1.39-10.49) and patients who acquire more rapid disease remissions (OR=9.91:95%CI=3.89-25.16) show a significant association with improvement of excellent quality of life. Having oral lesions associated with moderate improvement of Quality of life. 40-60 years age group and female gender are identified as more susceptible factors for AIBD. Among AIBD, highest prevalence is demonstrated by Pemphigus Vulgaris. An extremely larger effect is created on the quality of life of AIBD patients. Quality of life is properly managed by the patients in the higher age group and patients with a higher income. A successful improvement in quality of life is achieved by the patients who initially present with a higher severity and patients who experience early remission. It is clearly demonstrated that it is possible to improve dermatological quality of life by managing the disease condition rationally and methodically. This knowledge should be used to conduct modifications in the health system in order to improve compliance of patients treated for AIBD.The autoimmune bullous diseases (AIBD) are a group of clinical conditions characterized by erosions and bullae of the skin and mucous membranes, which can be prolonging to serious concerns for patients in their activities of daily living (ADL) and adversely affect their quality of life. Descriptive cross - sectional study design was conducted in dermatology clinic at National Hospital Colombo. 121 participants more than 18 years old were included. Non-probability, consecutive sampling technique was used to collect the study sample. Interviewer-administered questionnaire included with dermatological quality of life index was used as study instrument. Most prevalent bullous disorder is pemphigus vulgaris (N=81:66.9%). Extremely larger effect was created on the quality of life of significant majority of the study participants due to the disease condition (N=80 ;66.1%). Highest effect on quality of life after treatments was created on PV patients (t=17.08: p<0.001). Majority of participants represented extensive disease severity scores (N=99:81.8%) at initial presentation. Participants who had significant disease severity at the end of the treatments (N=15:12.4%) showed moderate and large improvement of quality of life. Majority of the study participants had reduced disease severity with treatment (Z>1.96:p<0.001). Majority of the study participants had detected side effects during the first two months following commencement of treatment. 62.8% (N=76) had experienced remission episodes of the disease condition. Age above 50 years (OR=2.75:95%CI=1.26-5.95), Patients with significant initial disease severity (OR=3.82:95%CI=1.39-10.49) and patients who acquire more rapid disease remissions (OR=9.91:95%CI=3.89-25.16) show a significant association with improvement of excellent quality of life. Having oral lesions associated with moderate improvement of Quality of life. 40-60 years age group and female gender are identified as more susceptible factors for AIBD. Among AIBD, highest prevalence is demonstrated by Pemphigus Vulgaris. An extremely larger effect is created on the quality of life of AIBD patients. Quality of life is properly managed by the patients in the higher age group and patients with a higher income. A successful improvement in quality of life is achieved by the patients who initially present with a higher severity and patients who experience early remission. It is clearly demonstrated that it is possible to improve dermatological quality of life by managing the disease condition rationally and methodically. This knowledge should be used to conduct modifications in the health system in order to improve compliance of patients treated for AIBD..
2023-01-01.
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